Metataxonomic Analysis of Individuals at BMI Extremes and Monozygotic Twins Discordant for BMI
نویسندگان
چکیده
منابع مشابه
Global Transcript Profiles of Fat in Monozygotic Twins Discordant for BMI: Pathways behind Acquired Obesity
BACKGROUND The acquired component of complex traits is difficult to dissect in humans. Obesity represents such a trait, in which the metabolic and molecular consequences emerge from complex interactions of genes and environment. With the substantial morbidity associated with obesity, a deeper understanding of the concurrent metabolic changes is of considerable importance. The goal of this study...
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e widespread availability of minimally invasive hemodynamic monitors encourages evaluation of cardiac output (CO) and stroke volume (SV) in real time, and they are integral to goal-directed therapy, algorithmbased treatment plans. Patients with extremes of body surface area (BSA) are at risk of having their indices erroneously evaluated despite adequate non-indexed values. We evaluated the use ...
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Childhood psychotic symptoms are associated with increased rates of schizophrenia, other psychiatric disorders, and suicide attempts in adulthood; thus, elucidating early risk indicators is crucial to target prevention efforts. There is considerable discordance for psychotic symptoms between monozygotic twins, indicating that child-specific non-genetic factors must be involved. Epigenetic proce...
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Aicardi syndrome is a developmental disorder characterised by agenesis of the corpus callosum, retinal lacunae, seizures, and developmental delay. It is believed to be X linked with lethality in males. We report a set of monozygotic female twins one of whom is healthy and intellectually normal while the other has the classical Aicardi phenotype with profound retardation. Family history is negat...
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ژورنال
عنوان ژورنال: Twin Research and Human Genetics
سال: 2018
ISSN: 1832-4274,1839-2628
DOI: 10.1017/thg.2018.26